A great beauty in her hometown,
Nezuko is a fair-skinned young girl, with long dark brown hair that reaches just below her waist, where it starts to take on a vermilion color at the elbows. A pink ribbon to the side tied her bangs together revealing her forehead. She has slanted downwards wide narrow eyebrows framing her face.

Notably she has long eyelashes covering her soft-looking pink eyes, gradually taking on a lighter color around the rims of the irises. The shape of her petite nose takes a slightly upturned appearance at the tip.

Nezuko is seen usually wearing a gag made of bamboo secured by red cloth around her jaw received from Giyu Tomioka.

When she transforms, she is able to squeeze her pupils down to narrow slits, while growing prominent fang and sharp nails that extend like claws, with tattoos around her body shaped like vines. Her veins pop out and a single horn protrudes on the side of her right forehead.

Nezuko is a kind and caring girl that takes care of her family, often helping with chores around the home. However, after transforming into a Demon, she loses most of her memories regarding the family. Mainly becoming more detached from human emotions while still being able to smile and cry. Compared to other Demons, she is calm and less malicious towards humans. She still retains her original caring and protective personality towards humans she feels as family. Her strong willpower is such that despite her circumstances as a human-eating demon, refuses to consume any flesh or blood. Although mostly forgetting how to speak, she uses expressive body language when communicating with others, and on rare occasions attempts speech.